Quantum Sensing: Necessity for low temperature and low vibrations-Most quantum states are only visible and controllable when the thermal energy KBT is comparable or smaller than the energy difference ΔE between the quantum states. Therefore, to see the quantum properties of materials or devices, they often need to be cooled to and maintained at millikelvin temperatures. In the last ten years, we have seen great progress in improving the accessibility to millikelvin environments via advanced cryogenic platforms offered by industry. On the basis of these platforms, the application can be developed that would allow probing quantum states of materials or devices, for example by means of Scanning Probe Microscopy (SPM) techniques. However, for low temperature SPM techniques, besides the low temperature, low vibrations are also essential. First, the interaction distance between probe and quantum state needs to be maintained and second, in case of force-sensors like M(R)FM, the sensor needs to be decoupled from force-noise due to accelerations. It is to this end that quantum sensing will require progression towards low temperature and low vibration environments to use quantum-enhanced probe sensors for opening a new paradigm of Scanning Probe Microscopy: qSPM.